{"id":1877,"date":"2020-05-21T08:01:06","date_gmt":"2020-05-21T08:01:06","guid":{"rendered":"https:\/\/www.cubasupport.ie\/latest\/?p=1877"},"modified":"2020-05-21T08:01:09","modified_gmt":"2020-05-21T08:01:09","slug":"cuba-develops-effective-peptide-against-covid-19","status":"publish","type":"post","link":"https:\/\/www.cubasupport.ie\/latest\/cuba-develops-effective-peptide-against-covid-19\/","title":{"rendered":"Cuba develops Effective Peptide Against COVID-19"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"340\" src=\"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/peptide-tab-.jpg?resize=600%2C340&#038;ssl=1\" alt=\"\" class=\"wp-image-1878\" srcset=\"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/peptide-tab-.jpg?w=600&amp;ssl=1 600w, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/peptide-tab-.jpg?resize=300%2C170&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/peptide-tab-.jpg?resize=388%2C220&amp;ssl=1 388w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption>Center for Genetic Engineering and Biotechnology (CIGB) laboratories, La Habana, Cuba. | Photo: Twitter\/@bohemiaonline<\/figcaption><\/figure><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">This protein increases its concentration during viral infections and inflammatory processes.<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Cuba\u2019s Center for Genetic Engineering and Biotechnology (CIGB) developed the CIGB-258, a new protein effective in Covid-19 treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cIt is an immunomodulatory peptide, derived from the cellular stress response protein, known as HSP60. This molecule was designed by bioinformatic tools and is obtained by chemical synthesis,\u201d affirmed CIGB\u2019s researcher Dr. Gillian Martinez Donato.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to Martinez, CIGB-258 operates in the regulation of the immune system. This protein increases its concentration during viral infections and inflammatory processes.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The CIGB requested the use of CIGB-258 in COVID confirmed patients in the severe and critical stages. Since May 5, 31 patients had received therapy with this peptide.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As Donato explained, 12 patients started CIGB-258 therapy intheir\u00a0\u00a0severe stages and 19 in the critical disease phase. In the first group, survival was 92 percent, while in the second group it was 73 percent.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>&#8220;Cuba&#8217;s Minister of Health, Jose Angel Portal Miranda, referred to the contributions of the-pharmaceutical and biotechnological industry, with innovative products for the treatment of the disease, such as recombinant Interferon alpha 2b, monoclonal antibodies, the CIGB-258 peptide and Surfacen.&#8221;&nbsp;<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>\u201cThis peptide is safe, with evidence of efficacy in an initial clinical study phase in patients with rheumatoid arthritis, by reducing the clinical activity associated with that condition, including synovitis and edema in the hands of patients,\u201d Martinez stated.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The CIGB submitted the request to the Cuban Center for Medicines, Equipment, and Medical Devices\u2019 Control (Cecmed) &nbsp;for its therapeutic use in confirmed patients of the COVID-19 in the severe and critical stages.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&nbsp;<br>\u201cA phase II clinical trial is currently underway in 187 patients with rheumatoid arthritis, and the results will be ready by the end of 2020,\u201d the CIGB specialist explained.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>So far, Cuba registered 1,881 positive cases of coronavirus, including 79 deaths, and 1,505 recoveries.\u00a0<\/p>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">Source: <a href=\"\/www.telesurenglish.net\" target=\"_blank\" rel=\"noreferrer noopener\">Telesur <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This protein increases its concentration during viral infections and inflammatory processes. Cuba\u2019s Center for Genetic Engineering and Biotechnology (CIGB) developed the CIGB-258, a new protein<a class=\"moretag\" href=\"https:\/\/www.cubasupport.ie\/latest\/cuba-develops-effective-peptide-against-covid-19\/\"> [&#8230;]<\/a><\/p>\n","protected":false},"author":101011,"featured_media":1878,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[36,8],"tags":[],"class_list":["post-1877","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","category-cuba"],"jetpack_publicize_connections":[],"jetpack-related-posts":[{"id":3083,"url":"https:\/\/www.cubasupport.ie\/latest\/cuba-develops-another-vaccine-against-the-coronavirus-and-it-is-not-injectable\/","url_meta":{"origin":1877,"position":0},"title":"Cuba develops another vaccine against the coronavirus and it is not injectable","author":"Editorial Team","date":"November 3, 2020","format":false,"excerpt":"Center for Genetic Engineering and Biotechnology (CIGB) of Cuba. Photo: Dunia \u00c1lvarez Palacios \/ Granma. The Cuban scientific community is working today on a third vaccine candidate against COVID-19,\u00a0the first that is not an injectable and would be applied nasal. Developed by the Center for Genetic Engineering and Biotechnology (CIGB),\u2026","rel":"","context":"In &quot;Covid-19&quot;","block_context":{"text":"Covid-19","link":"https:\/\/www.cubasupport.ie\/latest\/category\/cuba\/covid-19\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/Centro-de-Ingenieria-Genetica-y-Biotecnologia-CIGB-de-Cuba-580x446-1.jpg?fit=580%2C446&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/Centro-de-Ingenieria-Genetica-y-Biotecnologia-CIGB-de-Cuba-580x446-1.jpg?fit=580%2C446&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/Centro-de-Ingenieria-Genetica-y-Biotecnologia-CIGB-de-Cuba-580x446-1.jpg?fit=580%2C446&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":3251,"url":"https:\/\/www.cubasupport.ie\/latest\/cuba-has-four-vaccine-candidates-against-covid-19-on-clinical-trials\/","url_meta":{"origin":1877,"position":1},"title":"Cuba has four vaccine candidates against Covid-19 on clinical trials","author":"Editorial Team","date":"November 27, 2020","format":false,"excerpt":"Cuba has registered four vaccine candidates against Covid-19 that are currently on clinical trials, after Mambisa and Abdala, developed by the Genetic Engineering and Biotechnology Center (CIGB), were authorized for this phase of the study.According to information released on social networks, the regulatory entity of Medicines, Equipment and Medical Devices\u2026","rel":"","context":"In &quot;Covid-19&quot;","block_context":{"text":"Covid-19","link":"https:\/\/www.cubasupport.ie\/latest\/category\/cuba\/covid-19\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/covid-vacine.jpg?fit=748%2C498&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/covid-vacine.jpg?fit=748%2C498&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/covid-vacine.jpg?fit=748%2C498&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/covid-vacine.jpg?fit=748%2C498&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":5550,"url":"https:\/\/www.cubasupport.ie\/latest\/cuba-ships-15-million-abdala-vaccines-to-venezuela\/","url_meta":{"origin":1877,"position":2},"title":"Cuba Ships 1,5 Million Abdala Vaccines To Venezuela","author":"Editorial Team","date":"November 24, 2021","format":false,"excerpt":"\"We want to cooperate with the coronavirus immunisation of this brother country's people, who suffer the consequences of the U.S. blockade,\" Cuban scientists stated.\u00a0 On Saturday, Cuba's Center for Genetic Engineering and Biotechnology (CIGB) announced the delivery of 1,5 million Abdala COVID-19 vaccines to Venezuela. \"We want to cooperate with\u2026","rel":"","context":"In &quot;Cuba&quot;","block_context":{"text":"Cuba","link":"https:\/\/www.cubasupport.ie\/latest\/category\/cuba\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/vene_abdala.jpg_1718483346.jpg?fit=600%2C340&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/vene_abdala.jpg_1718483346.jpg?fit=600%2C340&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/vene_abdala.jpg_1718483346.jpg?fit=600%2C340&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":3883,"url":"https:\/\/www.cubasupport.ie\/latest\/cubas-abdala-vaccine-to-begin-phase-iii-of-clinical-trials\/","url_meta":{"origin":1877,"position":3},"title":"Cuba&#8217;s Abdala Vaccine to Begin Phase III of Clinical Trials","author":"Editorial Team","date":"March 10, 2021","format":false,"excerpt":"The Center for Genetic Engineering and Biotechnology\u00a0will guarantee\u00a0the doses needed for this clinical trial in which\u00a042,000 people will take\u00a0part. Cuba's President Miguel Diaz-Canel\u00a0on Saturday informed that the Abdala vaccine will start phase III of clinical trials this week in the provinces of Santiago de Cuba and Guantanamo. \"We are one\u2026","rel":"","context":"In &quot;Featured&quot;","block_context":{"text":"Featured","link":"https:\/\/www.cubasupport.ie\/latest\/category\/news\/featured\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/havana-1.jpeg?fit=1200%2C801&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/havana-1.jpeg?fit=1200%2C801&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/havana-1.jpeg?fit=1200%2C801&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/havana-1.jpeg?fit=1200%2C801&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/havana-1.jpeg?fit=1200%2C801&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":4747,"url":"https:\/\/www.cubasupport.ie\/latest\/cubas-soberana-02-covid-19-vaccine-to-reach-95-efficiency\/","url_meta":{"origin":1877,"position":4},"title":"Cuba&#8217;s Soberana 02 COVID-19 Vaccine To Reach 95% Efficiency","author":"Editorial Team","date":"June 27, 2021","format":false,"excerpt":"The\u00a0clinical trial's\u00a0preliminary results show a significant increase in the immune responses of patients between the second and third doses. On Thursday, Cuba\u2019s Finlay Vaccine Institute announced that its Soberana 02 COVID-19 vaccine is most likely to reach\u00a0up to\u00a095 percent efficiency in third phase of clinical trials. FVI scientist Maria Toledo\u2026","rel":"","context":"In &quot;Featured&quot;","block_context":{"text":"Featured","link":"https:\/\/www.cubasupport.ie\/latest\/category\/news\/featured\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/IMG_8872.jpg?fit=708%2C945&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/IMG_8872.jpg?fit=708%2C945&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/IMG_8872.jpg?fit=708%2C945&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/IMG_8872.jpg?fit=708%2C945&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":2146,"url":"https:\/\/www.cubasupport.ie\/latest\/interferon-in-cuba-a-prophecy-come-true\/","url_meta":{"origin":1877,"position":5},"title":"Interferon in Cuba, a prophecy come true","author":"Editorial Team","date":"June 16, 2020","format":false,"excerpt":"Fidel inaugurated the Center for Genetic Engineering and Biotechnology in 1986, where interferon was first produced 39 years ago, now playing a key role in the COVID-19 battle The Heberferon project was a colossal, rewarding effort that has saved lives.\u00a0Photo:\u00a0Ariel Cecilio Lemus Alvarez When Comandante en Jefe Fidel Castro inaugurated\u2026","rel":"","context":"In &quot;Covid-19&quot;","block_context":{"text":"Covid-19","link":"https:\/\/www.cubasupport.ie\/latest\/category\/cuba\/covid-19\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/inferon.jpg?fit=700%2C444&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/inferon.jpg?fit=700%2C444&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/inferon.jpg?fit=700%2C444&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/inferon.jpg?fit=700%2C444&ssl=1&resize=700%2C400 2x"},"classes":[]}],"jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p3xdTY-uh","jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.cubasupport.ie\/latest\/wp-content\/uploads\/peptide-tab-.jpg?fit=600%2C340&ssl=1","_links":{"self":[{"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/posts\/1877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/users\/101011"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/comments?post=1877"}],"version-history":[{"count":0,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/posts\/1877\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/media\/1878"}],"wp:attachment":[{"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/media?parent=1877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/categories?post=1877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cubasupport.ie\/latest\/wp-json\/wp\/v2\/tags?post=1877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}